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A Novel Murine Model Expressing a Chimeric mSCARB2/hSCARB2 Receptor Is Highly Susceptible to Oral Infection with Clinical Isolates of Enterovirus 71

Enterovirus 71 (EV71) infection is generally associated with hand-foot-and-mouth disease (HFMD) and may cause severe neurological disorders and even death. An effective murine oral infection model for studying the pathogenesis of various clinical EV71 isolates is lacking. We developed a transgenic (...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Yang, Cheng-Hung, Liang, Chung-Tiang, Jiang, Si-Tse, Chen, Kuan-Hsing, Yang, Chun-Chiao, Cheng, Mei-Ling, Ho, Hung-Yao
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6532076/
https://ncbi.nlm.nih.gov/pubmed/30894476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00183-19
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