Microcin PDI Inhibits Antibiotic-Resistant Strains of Escherichia coli and Shigella through a Mechanism of Membrane Disruption and Protection by Homotrimer Self-Immunity

Microcin PDI (MccPDI), a class IIa microcin that is produced by Escherichia coli strains 25 and 284, is known to inhibit foodborne pathogenic enterohemorrhagic E. coli serotypes O157:H7 and O26. Here we demonstrate that MccPDI can inhibit Shigella strains and E. coli isolates that are multidrug resi...

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Bibliografiske detaljer
Udgivet i:Appl Environ Microbiol
Main Authors: Lu, Shao-Yeh, Graça, Telmo, Avillan, Johannetsy J., Zhao, Zhe, Call, Douglas R.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2019
Fag:
Environmental Microbiology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6532030/
https://ncbi.nlm.nih.gov/pubmed/30902857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.00371-19
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