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Within-host evolution of Helicobacter pylori shaped by niche-specific adaptation, intragastric migrations and selective sweeps

The human pathogen Helicobacter pylori displays extensive genetic diversity. While H. pylori is known to evolve during infection, population dynamics inside the gastric environment have not been extensively investigated. Here we obtained gastric biopsies from multiple stomach regions of 16 H. pylori...

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Bibliografiske detaljer
Udgivet i:Nat Commun
Main Authors: Ailloud, Florent, Didelot, Xavier, Woltemate, Sabrina, Pfaffinger, Gudrun, Overmann, Jörg, Bader, Ruth Christiane, Schulz, Christian, Malfertheiner, Peter, Suerbaum, Sebastian
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2019
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6531487/
https://ncbi.nlm.nih.gov/pubmed/31118420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-10050-1
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