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Angiotensin II-mediated MYH9 downregulation causes structural and functional podocyte injury in diabetic kidney disease

MYH9, a widely expressed gene encoding nonmuscle myosin heavy chain, is also expressed in podocytes and is associated with glomerular pathophysiology. However, the mechanisms underlying MYH9-related glomerular diseases associated with proteinuria are poorly understood. Therefore, we investigated the...

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Dettagli Bibliografici
Pubblicato in:Sci Rep
Autori principali: Kang, Jeong Suk, Lee, Seung Joo, Lee, Ji-Hye, Kim, Ji-Hee, Son, Seung Seob, Cha, Seung-Kuy, Lee, Eun Soo, Chung, Choon Hee, Lee, Eun Young
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6531474/
https://ncbi.nlm.nih.gov/pubmed/31118506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-44194-3
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