Injectable polypeptide hydrogel-based co-delivery of vaccine and immune checkpoint inhibitors improves tumor immunotherapy

Immunotherapy, an attractive option for cancer treatment, necessitates the direct stimulation of immune cells in vivo and the simultaneous effective inhibition of immunosuppressive tumor microenvironments. Methods: In the present study, we developed an injectable PEG-b-poly(L-alanine) hydrogel for c...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Theranostics
Hauptverfasser: Song, Huijuan, Yang, Pengxiang, Huang, Pingsheng, Zhang, Chuangnian, Kong, Deling, Wang, Weiwei
Format: Artigo
Sprache:Inglês
Veröffentlicht: Ivyspring International Publisher 2019
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6531311/
https://ncbi.nlm.nih.gov/pubmed/31149045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.30577
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