Preclinical efficacy of hK2 targeted [(177)Lu]hu11B6 for prostate cancer theranostics

Androgen ablating drugs increase life expectancy in men with metastatic prostate cancer, but resistance inevitably develops. In a majority of these recurrent tumors, the androgen axis is reactivated in the form of increased androgen receptor (AR) expression. Targeting proteins that are expressed as...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Theranostics
Prif Awduron: Timmermand, Oskar Vilhelmsson, Elgqvist, Jörgen, Beattie, Kai A., Örbom, Anders, Larsson, Erik, Eriksson, Sophie E., Thorek, Daniel L.J., Beattie, Bradley J., Tran, Thuy A., Ulmert, David, Strand, Sven-Erik
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Ivyspring International Publisher 2019
Pynciau:
Research Paper
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6531309/
https://ncbi.nlm.nih.gov/pubmed/31149033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.31179
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