Myeloid cell-derived LL-37 promotes lung cancer growth by activating Wnt/β-catenin signaling

Rationale: Antimicrobial peptides, such as cathelicidin LL-37/hCAP-18, are important effectors of the innate immune system with direct antibacterial activity. In addition, LL-37 is involved in the regulation of tumor cell growth. However, the molecular mechanisms underlying the functions of LL-37 in...

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Veröffentlicht in:Theranostics
Hauptverfasser: Ji, Ping, Zhou, Yongxin, Yang, Yibao, Wu, Junlu, Zhou, Hao, Quan, Wenqiang, Sun, Junjun, Yao, Yiwen, Shang, Anquan, Gu, Chenzheng, Zeng, Bingjie, Firrman, Jenni, Xiao, Weidong, Bals, Robert, Sun, Zujun, Li, Dong
Format: Artigo
Sprache:Inglês
Veröffentlicht: Ivyspring International Publisher 2019
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6531301/
https://ncbi.nlm.nih.gov/pubmed/31149039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.30726
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