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Accurate and Efficient P-value Calculation via Gaussian Approximation: a Novel Monte-Carlo Method

It is of fundamental interest in statistics to test the significance of a set of covariates. For example, in genome-wide association studies, a joint null hypothesis of no genetic effect is tested for a set of multiple genetic variants. The minimum p-value method, higher criticism, and Berk–Jones te...

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Vydáno v:J Am Stat Assoc
Hlavní autoři: Liu, Yaowu, Xie, Jun
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6530914/
https://ncbi.nlm.nih.gov/pubmed/31130762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/01621459.2017.1407776
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