Brain IGFBP-5 Modifies the Relation of Depressive Symptoms to Decline in Working Memory in Older Persons

BACKGROUND: Brain proteins, including Insulin-like Growth Factor Binding Protein 5 (IGFBP-5), have been associated with cognitive dysfunction in aging. Mechanisms linking depression with cognition are poorly understood. We hypothesize that the association of depressive symptoms with cognition is med...

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Detalhes bibliográficos
Publicado no:J Affect Disord
Main Authors: Capuano, Ana W., Wilson, Robert S., Honer, William G., Petyuk, Vladislav A., Leurgans, Sue E., Yu, Lei, Gatchel, Jennifer R., Arnold, Steven, Bennett, David A., Arvanitakis, Zoe
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6530787/
https://ncbi.nlm.nih.gov/pubmed/30875674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jad.2019.03.051
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