Abscopal Effects in Radio-Immunotherapy—Response Analysis of Metastatic Cancer Patients With Progressive Disease Under Anti-PD-1 Immune Checkpoint Inhibition

Immune checkpoint inhibition (ICI) targeting the programmed death receptor 1 (PD-1) has shown promising results in the fight against cancer. Systemic anti-tumor reactions due to radiation therapy (RT) can lead to regression of non-irradiated lesions (NiLs), termed “abscopal effect” (AbE). Combinatio...

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Detalles Bibliográficos
Publicado en:Front Pharmacol
Main Authors: Trommer, Maike, Yeo, Sin Yuin, Persigehl, Thorsten, Bunck, Anne, Grüll, Holger, Schlaak, Max, Theurich, Sebastian, von Bergwelt-Baildon, Michael, Morgenthaler, Janis, Herter, Jan M., Celik, Eren, Marnitz, Simone, Baues, Christian
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2019
Assuntos:
Pharmacology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6530339/
https://ncbi.nlm.nih.gov/pubmed/31156434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.00511
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