Age-Dependent Oxidative Stress Elevates Arginase 1 and Uncoupled Nitric Oxide Synthesis in Skeletal Muscle of Aged Mice

Aging is associated with reduced muscle mass (sarcopenia) and poor bone quality (osteoporosis), which together increase the incidence of falls and bone fractures. It is widely appreciated that aging triggers systemic oxidative stress, which can impair myoblast cell survival and differentiation. We p...

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Detalhes bibliográficos
Publicado no:Oxid Med Cell Longev
Main Authors: Pandya, Chirayu D., Lee, Byung, Toque, Haroldo A., Mendhe, Bharati, Bragg, Robert T., Pandya, Bhaumik, Atawia, Reem T., Isales, Carlos, Hamrick, Mark, Caldwell, R. William, Fulzele, Sadanand
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6530149/
https://ncbi.nlm.nih.gov/pubmed/31205583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/1704650
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