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Effect of Dapagliflozin Treatment on the Expression of Renal Sodium Transporters/Channels on High-Fat Diet Diabetic Mice

BACKGROUND: Inhibition of the Na(+)/glucose co-transporter 2 is a new therapeutic strategy for diabetes. It is unclear how proximal loss of Na(+) (and glucose) affects the subsequent Na(+) transporters in the proximal tubule (PT), thick ascending limb of loop of Henle (TAL), distal convoluted tubule...

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Détails bibliographiques
Publié dans:Nephron Clin Pract
Auteurs principaux: Ma, Chao, de Baaij, Jeroen H.F., Millar, Paul J., Gault, Victor A., de Galan, Bastiaan E., Bindels, René J.M., Hoenderop, Joost G.J.
Format: Artigo
Langue:Inglês
Publié: S. Karger AG 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6530118/
https://ncbi.nlm.nih.gov/pubmed/30799406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000496617
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