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Retinal and Corneal Toxicity and Pharmacokinetic Analysis of Intraocular Injection of Ganciclovir in Rabbit Eyes

PURPOSE: To evaluate the safety and pharmacokinetic changes of ganciclovir (GCV) intraocular injection. METHODS: GCV (2 mg/0.1 mL) was injected into rabbit eyes. Aqueous GCV concentration was detected by high-performance liquid chromatography. Potential toxicity was assessed by slit-lamp examination...

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Detalhes bibliográficos
Publicado no:J Ophthalmol
Main Authors: Sun, Bin-jia, Peng, Rong-mei, Lu, Qing, Hong, Jing
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6530113/
https://ncbi.nlm.nih.gov/pubmed/31205782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/3054758
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