A randomised controlled trial of matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDITOF-MS) versus conventional microbiological methods for identifying pathogens: Impact on optimal antimicrobial therapy of invasive bacterial and fungal infections in Vietnam

OBJECTIVES: We assessed the impact of MALDITOF-MS on the timeliness of optimal antimicrobial therapy through a parallel-arm randomised controlled trial in two hospitals in Vietnam. METHODS: We recruited patients with a pathogen (bacterial or fungal) cultured from a normally sterile sample. Samples w...

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Udgivet i:J Infect
Main Authors: Nadjm, Behzad, Dat, Vu Quoc, Campbell, James I., Dung, Vu Tien Viet, Torre, Alessandro, Tu, Nguyen Thi Cam, Van, Ninh Thi Thanh, Trinh, Dao Tuyet, Lan, Nguyen Phu Huong, Trung, Nguyen Vu, Hang, Nguyen Thi Thuy, Hoi, Le Thi, Baker, Stephen, Wolbers, Marcel, Chau, Nguyen Van Vinh, Van Kinh, Nguyen, Thwaites, Guy E., van Doorn, H. Rogier, Wertheim, Heiman F.L.
Format: Artigo
Sprog:Inglês
Udgivet: W.B. Saunders 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6529875/
https://ncbi.nlm.nih.gov/pubmed/30914268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jinf.2019.03.010
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