Hippocampal Mossy Fibers Synapses in CA3 Pyramidal Cells Are Altered at an Early Stage in a Mouse Model of Alzheimer's Disease

Early Alzheimer's disease (AD) affects the brain non-uniformly, causing hippocampal memory deficits long before wide-spread brain degeneration becomes evident. Here we addressed whether mossy fiber inputs from the dentate gyrus onto CA3 principal cells are affected in an AD mouse model before a...

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Veröffentlicht in:J Neurosci
Hauptverfasser: Viana da Silva, Silvia, Zhang, Pei, Haberl, Matthias Georg, Labrousse, Virginie, Grosjean, Noëlle, Blanchet, Christophe, Frick, Andreas, Mulle, Christophe
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for Neuroscience 2019
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Research Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6529872/
https://ncbi.nlm.nih.gov/pubmed/30886015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2868-18.2019
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