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PARP1 Inhibition as a Novel Therapeutic Target for Keloid Disease
Objective: Inactivation of poly(ADP-ribose) polymerase 1 (PARP1) has been found to have protective effect in several fibrotic diseases. But the effect is not studied yet in keloids. Herein, we evaluated the therapeutic effect of PARP1 inhibitor, rucaparib, for keloids. Approach: The protein expressi...
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| Publicado no: | Adv Wound Care (New Rochelle) |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Mary Ann Liebert, Inc., publishers
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6529855/ https://ncbi.nlm.nih.gov/pubmed/31119062 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/wound.2018.0910 |
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