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Are There Common Mechanisms Between the Hutchinson–Gilford Progeria Syndrome and Natural Aging?

The Hutchinson–Gilford progeria syndrome (HGPS) is a premature aging disease caused by mutations of the LMNA gene leading to increased production of a partially processed form of the nuclear fibrillar protein lamin A – progerin. Progerin acts as a dominant factor that leads to multiple morphological...

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Detalhes bibliográficos
Publicado no:Front Genet
Main Authors: Ashapkin, Vasily V., Kutueva, Lyudmila I., Kurchashova, Svetlana Y., Kireev, Igor I.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6529819/
https://ncbi.nlm.nih.gov/pubmed/31156709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2019.00455
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