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Red Blood Cell Homeostasis and Altered Vesicle Formation in Patients With Paroxysmal Nocturnal Hemoglobinuria

A subset of the red blood cells (RBCs) of patients with paroxysmal nocturnal hemoglobinuria (PNH) lacks GPI-anchored proteins. Some of these proteins, such as CD59, inhibit complement activation and protect against complement-mediated lysis. This pathology thus provides the possibility to explore th...

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Publicat a:Front Physiol
Autors principals: Freitas Leal, Joames K., Preijers, Frank, Brock, Roland, Adjobo-Hermans, Merel, Bosman, Giel
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6529780/
https://ncbi.nlm.nih.gov/pubmed/31156458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2019.00578
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