Combining Monophosphoryl Lipid A (MPL), CpG Oligodeoxynucleotide (ODN), and QS-21 Adjuvants Induces Strong and Persistent Functional Antibodies and T Cell Responses against Cell-Traversal Protein for Ookinetes and Sporozoites (CelTOS) of Plasmodium falciparum in BALB/c Mice

Plasmodium falciparum cell-traversal protein for ookinetes and sporozoites (PfCelTOS) is an advanced vaccine candidate that has a crucial role in the traversal of the malaria parasite in both mosquito and mammalian hosts. As recombinant purified proteins are normally poor immunogens, they require to...

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Bibliographische Detailangaben
Veröffentlicht in:Infect Immun
Hauptverfasser: Pirahmadi, Sakineh, Zakeri, Sedigheh, Mehrizi, Akram A., Djadid, Navid D., Raz, Abbas-Ali, Sani, Jafar J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2019
Schlagworte:
Fungal and Parasitic Infections
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6529666/
https://ncbi.nlm.nih.gov/pubmed/30936155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00911-18
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