Implantable hyaluronic acid-deferoxamine conjugate prevents nonunions through stimulation of neovascularization

Approximately 6.3 million fractures occur in the U.S. annually, with 5–10% resulting in debilitating nonunions. A major limitation to achieving successful bony union is impaired neovascularization. To augment fracture healing, we designed an implantable drug delivery technology containing the angiog...

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Udgivet i:NPJ Regen Med
Main Authors: Donneys, Alexis, Yang, Qiuhong, Forrest, Marcus Laird, Nelson, Noah S., Zhang, Ti, Ettinger, Russell, Ranganathan, Kavitha, Snider, Alicia, Deshpande, Sagar S., Cohen, Mark S., Buchman, Steven R.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6529413/
https://ncbi.nlm.nih.gov/pubmed/31123600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41536-019-0072-9
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