Expression profiling of immune inhibitory Siglecs and their ligands in patients with glioma

Gliomas appear to be highly immunosuppressive tumors, with a strong myeloid component. This includes MDSCs, which are a heterogeneous, immature myeloid cell population expressing myeloid markers Siglec-3 (CD33) and CD11b and lacking markers of mature myeloid cells including MHC II. Siglec-3 is a mem...

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Detalhes bibliográficos
Publicado no:Cancer Immunol Immunother
Main Authors: Santegoets, Kim C. M., Gielen, Paul R., Büll, Christian, Schulte, Barbara M., Kers-Rebel, Esther D., Küsters, Benno, Bossman, Sandra A. J. F. H., ter Laan, Mark, Wesseling, Pieter, Adema, Gosse J.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2019
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6529385/
https://ncbi.nlm.nih.gov/pubmed/30953118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00262-019-02332-w
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