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Targeting STT3A-oligosaccharyltransferase with NGI-1 causes herpes simplex virus 1 dysfunction

Herpes simplex virus 1 (HSV-1) is a contagious neurotropic herpesvirus responsible for oral lesions and herpesviral encephalitis. The HSV-1 envelope contains N-glycosylated proteins involved in infection and that are candidate drug targets. NGI-1 is a small-molecule inhibitor of oligosaccharyltransf...

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Bibliographische Detailangaben
Veröffentlicht in:FASEB J
Hauptverfasser: Lu, Hua, Cherepanova, Natalia A., Gilmore, Reid, Contessa, Joseph N., Lehrman, Mark A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Federation of American Societies for Experimental Biology 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6529348/
https://ncbi.nlm.nih.gov/pubmed/30811219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201802044RR
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