Examination of the role of sphingosine kinase 2 in a murine model of systemic lupus erythematosus

Systemic lupus erythematosus is an autoimmune disease characterized by overproduction of type 1 IFN that causes multiple organ dysfunctions. Plasmacytoid dendritic cells (pDCs) that secrete large amounts of IFN have recently been implicated in the initiation of the disease in preclinical mouse model...

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Veröffentlicht in:FASEB J
Hauptverfasser: Mohammed, Sabira, Vineetha, Nalanda S., James, Shirley, Aparna, Jayasekharan S., Lankadasari, Manendra Babu, Allegood, Jeremy C., Li, Quan-Zhen, Spiegel, Sarah, Harikumar, Kuzhuvelil B.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Federation of American Societies for Experimental Biology 2019
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Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6529345/
https://ncbi.nlm.nih.gov/pubmed/30840833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201802535R
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