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Impact of branching on the conformational heterogeneity of the lipopolysaccharide from Klebsiella pneumoniae: Implications for vaccine design

Resistance of Klebsiella pneumoniae (KP) to antibiotics has motivated the development of an efficacious KP human vaccine that would not be subject to antibiotic resistance. Klebsiella lipopolysaccharide (LPS) associated O polysaccharide (OPS) types have provoked broad interest as a vaccine antigen a...

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Detalhes bibliográficos
Publicado no:Carbohydr Res
Main Authors: Aytenfisu, Asaminew H., Simon, Raphael, MacKerell, Alexander D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6529184/
https://ncbi.nlm.nih.gov/pubmed/30818097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.carres.2019.02.003
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