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Inhibition of adipose tissue PPARγ prevents increased adipocyte expansion after lipectomy and exacerbates a glucose‐intolerant phenotype

OBJECTIVES: Adipose tissue plays a fundamental role in glucose homeostasis. For example, fat removal (lipectomy, LipX) in lean mice, resulting in a compensatory 50% increase in total fat mass, is associated with significant improvement in glucose tolerance. This study was designed to further examine...

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Vydáno v:Cell Prolif
Hlavní autoři: Booth, A. D., Magnuson, A. M., Cox‐York, K. A., Wei, Y., Wang, D., Pagliassotti, M. J., Foster, M. T.
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6529148/
https://ncbi.nlm.nih.gov/pubmed/27976431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cpr.12325
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