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Combined Erlotinib and PF‐03084014 treatment contributes to synthetic lethality in head and neck squamous cell carcinoma

OBJECTIVES: Head and neck squamous cell carcinoma (HNSCC) is characterized by high mortality and low survival rates. As an epidermal growth factor receptor (EGFR) inhibitor, Erlotinib has been approved for treatment of various tumours. PF‐03084014 is a selective inhibitor of Notch1 signalling. This...

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Bibliografski detalji
Izdano u:Cell Prolif
Glavni autori: Zheng, Yang, Wang, Zhao, Ding, Xu, Dong, Yibo, Zhang, Wei, Zhong, Yi, Gu, Wenyi, Wu, Yunong, Song, Xiaomeng
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2017
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6528911/
https://ncbi.nlm.nih.gov/pubmed/29232766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cpr.12424
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