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Solid-to-fluid DNA transition inside HSV-1 capsid close to the temperature of infection

DNA in the human Herpes simplex virus type 1 (HSV-1) capsid is packaged to a tight density. This leads to tens of atmospheres of internal pressure responsible for the delivery of the herpes genome into the cell nucleus. In this study we show that, despite its liquid crystalline state inside the caps...

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Dettagli Bibliografici
Pubblicato in:Nat Chem Biol
Autori principali: Sae-Ueng, Udom, Li, Dong, Zuo, Xiaobing, Huffman, Jamie B, Homa, Fred L, Rau, Donald, Evilevitch, Alex
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6528806/
https://ncbi.nlm.nih.gov/pubmed/25195012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.1628
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