Structural Mimicry by a Bacterial F Box Effector Hijacks the Host Ubiquitin-Proteasome System

Ankyrin B (AnkB/LegAU13) is a translocated F box effector essential for the intracellular replication of the pathogen Legionella pneumophila. AnkB co-opts a host ubiquitin ligase to decorate the pathogen-containing vacuole with K(48)-linked polyubiquitinated proteins and degrade host proteins as a s...

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Bibliographic Details
Published in:Structure
Main Authors: Wong, Kathy, Perpich, John D., Kozlov, Guennadi, Cygler, Miroslaw, Kwaik, Yousef Abu, Gehring, Kalle
Format: Artigo
Language:Inglês
Published: 2017
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6528793/
https://ncbi.nlm.nih.gov/pubmed/28111017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2016.12.015
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