Evaluation of lentinan effects on cytochrome P450 activity in rats by a cocktail method

OBJECTIVE(S): In this study, a cocktail of probe drugs was used to assess whether lentinan could influence the activities of rat enzymes CYP3A4, CYP2D6, CYP1A2, CYP2C19, and CYP2C9 in vivo. MATERIALS AND METHODS: Fourteen days after intraperitoneal injection of lentinan, rats were given an oral dose...

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Vydáno v:Iran J Basic Med Sci
Hlavní autoři: Lin, Yiping, Wei, Yanli, Hu, Xiaoxia, Wu, Meiling, Yao, Jingchan, Ying, Xiaoqian, Fu, Xiaoyan, Ding, Mingxing, Qiao, Liman
Médium: Artigo
Jazyk:Inglês
Vydáno: Mashhad University of Medical Sciences 2019
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6528719/
https://ncbi.nlm.nih.gov/pubmed/31156791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.22038/ijbms.2019.31611.7611
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