Novel Benzodiazepine-Like Ligands with Various Anxiolytic, Antidepressant, or Pro-Cognitive Profiles

Altered gamma-aminobutyric acid (GABA) function is consistently reported in psychiatric disorders, normal aging, and neurodegenerative disorders and reduced function of GABA interneurons is associated with both mood and cognitive symptoms. Benzodiazepines (BZ) have broad anxiolytic, but also sedativ...

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Detalhes bibliográficos
Publicado no:Mol Neuropsychiatry
Main Authors: Prevot, Thomas D., Li, Guanguan, Vidojevic, Aleksandra, Misquitta, Keith A., Fee, Corey, Santrac, Anja, Knutson, Daniel E., Stephen, Michael Rajesh, Kodali, Revathi, Zahn, Nicolas M., Arnold, Leggy A., Scholze, Petra, Fisher, Janet L., Marković, Bojan D., Banasr, Mounira, Cook, James M., Savic, Miroslav, Sibille, Etienne
Formato: Artigo
Idioma:Inglês
Publicado em: S. Karger AG 2019
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Original Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6528097/
https://ncbi.nlm.nih.gov/pubmed/31192221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000496086
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