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Long QT Syndrome Modelling with Cardiomyocytes Derived from Human-induced Pluripotent Stem Cells

Long QT syndrome (LQTS) is a potentially severe arrhythmogenic disorder, associated with a prolonged QT interval and sudden death, caused by mutations in key genes regulating cardiac electrophysiology. Current strategies to study LQTS in vitro include heterologous systems or animal models. Despite t...

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Bibliografske podrobnosti
izdano v:Arrhythm Electrophysiol Rev
Main Authors: Sala, Luca, Gnecchi, Massimiliano, Schwartz, Peter J
Format: Artigo
Jezik:Inglês
Izdano: Radcliffe Cardiology 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6528025/
https://ncbi.nlm.nih.gov/pubmed/31114684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15420/aer.2019.1.1
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