Stem Cell Based Drug Delivery for Protection of Auditory Neurons in a Guinea Pig Model of Cochlear Implantation

Background: The success of a cochlear implant (CI), which is the standard therapy for patients suffering from severe to profound sensorineural hearing loss, depends on the number and excitability of spiral ganglion neurons (SGNs). Brain-derived neurotrophic factor (BDNF) has a protective effect on S...

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Pubblicato in:Front Cell Neurosci
Autori principali: Scheper, Verena, Hoffmann, Andrea, Gepp, Michael M., Schulz, André, Hamm, Anika, Pannier, Christoph, Hubka, Peter, Lenarz, Thomas, Schwieger, Jana
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2019
Soggetti:
Neuroscience
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6527816/
https://ncbi.nlm.nih.gov/pubmed/31139049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2019.00177
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