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Clinical utility of pembrolizumab in the management of advanced solid tumors: an evidence-based review on the emerging new data

Pembrolizumab is a full-length human immunoglobulin G4 (IgG4) monoclonal antibody directed against the immune checkpoint PD-1 to remove its binding with PD-L1 and thus to restore an anti-tumor immune response of T cells. Pembrolizumab is one of the most advanced immune checkpoint inhibitors for canc...

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Detalhes bibliográficos
Publicado no:Cancer Manag Res
Main Authors: du Rusquec, Pauline, de Calbiac, Ombline, Robert, Marie, Campone, Mario, Frenel, Jean Sebastien
Formato: Artigo
Idioma:Inglês
Publicado em: Dove 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6527794/
https://ncbi.nlm.nih.gov/pubmed/31190995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CMAR.S151023
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