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Epigenetic therapy of Prader–Willi syndrome
Prader–Willi syndrome (PWS) is a complex and multisystem neurobehavioral disorder. The molecular mechanism of PWS is deficiency of paternally expressed genes from the chromosome 15q11-q13. Due to imprinted gene regulation, the same genes in the maternal chromosome 15q11-q13 are structurally intact b...
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| 出版年: | Transl Res |
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| 主要な著者: | , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2019
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6527448/ https://ncbi.nlm.nih.gov/pubmed/30904443 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.trsl.2019.02.012 |
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