Chronic pain in adults with sickle cell disease is associated with alterations in functional connectivity of the brain

Chronic pain affects 50% of adults with sickle cell disease (SCD). Although central sensitization is thought to contribute to the pathogenesis of this chronic pain, no studies have examined differences in functional connectivity of the brain between patients with SCD with and without chronic pain. W...

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Bibliographic Details
Published in:PLoS One
Main Authors: Karafin, Matthew S., Chen, Guangyu, Wandersee, Nancy J., Brandow, Amanda M., Hurley, Robert W., Simpson, Pippa, Ward, Doug, Li, Shi-Jiang, Field, Joshua J.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2019
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6527293/
https://ncbi.nlm.nih.gov/pubmed/31107926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0216994
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