Carvedilol inhibits EGF-mediated JB6 P+ colony formation through a mechanism independent of adrenoceptors

Carvedilol is reported to prevent cancers in humans and animal models. However, a molecular mechanism has yet to be established, and the extent to which other β-blockers are chemopreventive remains relatively unknown. A comparative pharmacological approach was utilized with the expectation that a me...

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Udgivet i:PLoS One
Main Authors: Cleveland, Kristan H., Liang, Sherry, Chang, Andy, Huang, Kevin M., Chen, Si, Guo, Lei, Huang, Ying, Andresen, Bradley T.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2019
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6527222/
https://ncbi.nlm.nih.gov/pubmed/31107911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0217038
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