The ATG5-binding and coiled coil domains of ATG16L1 maintain autophagy and tissue homeostasis in mice independently of the WD domain required for LC3-associated phagocytosis

Macroautophagy/autophagy delivers damaged proteins and organelles to lysosomes for degradation, and plays important roles in maintaining tissue homeostasis by reducing tissue damage. The translocation of LC3 to the limiting membrane of the phagophore, the precursor to the autophagosome, during autop...

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Detalhes bibliográficos
Publicado no:Autophagy
Main Authors: Rai, Shashank, Arasteh, Maryam, Jefferson, Matthew, Pearson, Timothy, Wang, Yingxue, Zhang, Weijiao, Bicsak, Bertalan, Divekar, Devina, Powell, Penny P., Naumann, Ronald, Beraza, Naiara, Carding, Simon R., Florey, Oliver, Mayer, Ulrike, Wileman, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2018
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6526875/
https://ncbi.nlm.nih.gov/pubmed/30403914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2018.1534507
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