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Diametric neural ensemble dynamics in parkinsonian and dyskinetic states

Loss of dopamine in Parkinson's disease is hypothesized to impede movement by inducing hypo- and hyperactivity in striatal spiny projection neurons (SPNs) of the direct (dSPNs) and indirect (iSPNs) pathways in the basal ganglia, respectively. The opposite imbalance might underlie hyperkinetic a...

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Detalhes bibliográficos
Publicado no:Nature
Main Authors: Parker, Jones G., Marshall, Jesse D., Ahanonu, Biafra, Wu, Yu-Wei, Kim, Tony Hyun, Grewe, Benjamin F., Zhang, Yanping, Li, Jin Zhong, Ding, Jun B., Ehlers, Michael D., Schnitzer, Mark J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6526726/
https://ncbi.nlm.nih.gov/pubmed/29720658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-018-0090-6
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