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Alternative splicing may not be the key to proteome complexity

Alternative splicing is commonly believed to be a major source of cellular protein diversity. However, although many thousands of alternatively spliced transcripts are routinely detected in RNAseq studies, reliable large-scale mass spectrometry-based proteomics studies identify only a small fraction...

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Bibliographic Details
Published in:Trends Biochem Sci
Main Authors: Tress, Michael L., Abascal, Federico, Valencia, Alfonso
Format: Artigo
Language:Inglês
Published: 2016
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6526280/
https://ncbi.nlm.nih.gov/pubmed/27712956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tibs.2016.08.008
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