Proposing a validation scheme for (13)C metabolite tracer studies in high-resolution mass spectrometry

(13)C metabolite tracer and metabolic flux analyses require upfront experimental planning and validation tools. Here, we present a validation scheme including a comparison of different LC methods that allow for customization of analytical strategies for tracer studies with regard to the targeted met...

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Dettagli Bibliografici
Pubblicato in:Anal Bioanal Chem
Autori principali: Schwaiger-Haber, Michaela, Hermann, Gerrit, El Abiead, Yasin, Rampler, Evelyn, Wernisch, Stefanie, Sas, Kelli, Pennathur, Subramaniam, Koellensperger, Gunda
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer Berlin Heidelberg 2019
Soggetti:
Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6526147/
https://ncbi.nlm.nih.gov/pubmed/30972471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00216-019-01773-7
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