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Kinetics of Transient Protein Complexes Determined via Diffusion-Independent Microfluidic Mixing and Fluorescence Stoichiometry

Low-affinity protein complexes and their transient states are difficult to measure in single-molecule experiments because of the requirement of low concentrations. A prominent solution to this problem is the use of microfluidic mixing devices, which rely on diffusion-based mixing of fluorescently la...

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Detalhes bibliográficos
Publicado no:J Phys Chem B
Main Authors: Hellenkamp, Björn, Thurn, Johann, Stadlmeier, Martina, Hugel, Thorsten
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6526119/
https://ncbi.nlm.nih.gov/pubmed/30351113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jpcb.8b07437
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