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Sodium arsenite exposure inhibits histone acetyltransferase p300 for attenuating H3K27ac at enhancers in mouse embryonic fibroblast cells

Both epidemiological investigations and animal studies have linked arsenic-contaminated water to cancers, including skin, liver and lung cancers. Besides genotoxicity, arsenic exposure-related pathogenesis of disease is widely considered through epigenetic mechanisms; however, the underlying mechani...

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Publicado en:Toxicol Appl Pharmacol
Main Authors: Zhu, Yan, Li, Yanqiang, Lou, Dan, Gao, Yang, Yu, Jing, Kong, Dehui, Zhang, Qiang, Jia, Yankai, Zhang, Haimou, Wang, Zhibin
Formato: Artigo
Idioma:Inglês
Publicado: 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6526104/
https://ncbi.nlm.nih.gov/pubmed/30130555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2018.08.011
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