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Upstream Signaling Events Leading to Elevated Production of Pro-Survival Nitric Oxide in Photodynamically-Challenged Glioblastoma Cells

Nitric oxide (NO) generated endogenously by inducible nitric oxide synthase (iNOS) promotes growth and migration/invasion of glioblastoma cells and also fosters resistance to chemotherapy and ionizing radiotherapy. Our recent studies revealed that glioblastoma cell iNOS/NO also opposes the cytotoxic...

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Detalhes bibliográficos
Publicado no:Free Radic Biol Med
Main Authors: Fahey, Jonathan M., Korytowski, Witold, Girotti, Albert W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6526063/
https://ncbi.nlm.nih.gov/pubmed/30991141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2019.04.013
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