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Engineering of L-Plastin Peptide-Loaded Biodegradable Nanoparticles for Sustained Delivery and Suppression of Osteoclast Function In Vitro

We have recently demonstrated that a small molecular weight amino-terminal peptide of L-plastin (10 amino acids; “MARGSVSDEE”) suppressed the phosphorylation of endogenous L-plastin. Therefore, the formation of nascent sealing zones (NSZs) and bone resorption are reduced. The aim of this study was t...

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Détails bibliographiques
Publié dans:Int J Cell Biol
Auteurs principaux: Majumdar, Sunipa, Wadajkar, Aniket S., Aljohani, Hanan, Reynolds, Mark A., Kim, Anthony J., Chellaiah, Meenakshi
Format: Artigo
Langue:Inglês
Publié: Hindawi 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6525930/
https://ncbi.nlm.nih.gov/pubmed/31191656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/6943986
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