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Selective isotope labeling for NMR structure determination of proteins in complex with unlabeled ligands

The physiological role of proteins is frequently linked to interactions with non-protein ligands or posttranslational modifications. Structural characterization of these complexes or modified proteins by NMR may be difficult as the ligands are usually not available in an isotope-labeled form and NMR...

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Vydáno v:J Biomol NMR
Hlavní autoři: Tripsianes, Konstantinos, Schütz, Ulrike, Emmanouilidis, Leonidas, Gemmecker, Gerd, Sattler, Michael
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer Netherlands 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6525670/
https://ncbi.nlm.nih.gov/pubmed/31041647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10858-019-00241-9
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