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Neutrophils Derived from Genetically Modified Human Induced Pluripotent Stem Cells Circulate and Phagocytose Bacteria In Vivo

Bacterial and fungal infections are a major cause of morbidity and mortality in neutropenic patients. Donor‐derived neutrophil transfusions have been used for prophylaxis or treatment for infection in neutropenic patients. However, the short half‐life and the limited availability of large numbers of...

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Detalhes bibliográficos
Publicado no:Stem Cells Transl Med
Main Authors: Trump, Lisa R., Nayak, Ramesh C., Singh, Abhishek K., Emberesh, Sana, Wellendorf, Ashley M., Lutzko, Carolyn M., Cancelas, Jose A.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6525559/
https://ncbi.nlm.nih.gov/pubmed/30793529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sctm.18-0255
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