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Pleiotropic neuroprotective effects of taxifolin in cerebral amyloid angiopathy

Cerebral amyloid angiopathy (CAA) results from amyloid-β deposition in the cerebrovasculature. It is frequently accompanied by Alzheimer’s disease and causes dementia. We recently demonstrated that in a mouse model of CAA, taxifolin improved cerebral blood flow, promoted amyloid-β removal from the b...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Inoue, Takayuki, Saito, Satoshi, Tanaka, Masashi, Yamakage, Hajime, Kusakabe, Toru, Shimatsu, Akira, Ihara, Masafumi, Satoh-Asahara, Noriko
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6525485/
https://ncbi.nlm.nih.gov/pubmed/31036637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1901659116
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