Interleukin-1-related activity and hypocretin-1 in cerebrospinal fluid contribute to fatigue in primary Sjögren’s syndrome

BACKGROUND: Fatigue is a common and sometimes debilitating phenomenon in primary Sjögren’s syndrome (pSS) and other chronic inflammatory diseases. We aimed to investigate how IL-1 β-related molecules and the neuropeptide hypocretin-1 (Hcrt1), a regulator of wakefulness, influence fatigue. METHODS: H...

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Detalles Bibliográficos
Publicado en:J Neuroinflammation
Main Authors: Bårdsen, Kjetil, Brede, Cato, Kvivik, Ingeborg, Kvaløy, Jan Terje, Jonsdottir, Kristin, Tjensvoll, Anne Bolette, Ruoff, Peter, Omdal, Roald
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2019
Assuntos:
Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6525358/
https://ncbi.nlm.nih.gov/pubmed/31101054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-019-1502-8
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