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Significance of sphingosine kinase 1 expression in feline mammary tumors
BACKGROUND: Sphingosine kinase 1 (SPHK1) is an enzyme that converts pro-apoptotic ceramide and sphingosine into anti-apoptotic sphingosine-1-phosphate. There is growing evidence that SPHK1 activation promotes oncogenic transformation, tumor growth, chemotherapy resistance, and metastatic spread. Hig...
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| Publicado en: | BMC Vet Res |
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| Autores principales: | , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
BioMed Central
2019
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6525354/ https://ncbi.nlm.nih.gov/pubmed/31101115 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12917-019-1883-z |
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