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Plk1 Mediates Paxillin Phosphorylation (Ser-272), Centrosome Maturation, and Airway Smooth Muscle Layer Thickening in Allergic Asthma

Allergic asthma is characterized by airway smooth muscle layer thickening, which is largely attributed to cell division that requires the formation of centrosomes. Centrosomes play a pivotal role in regulating bipolar spindle formation and cell division. Before mitosis, centrosomes undergo maturatio...

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Dettagli Bibliografici
Pubblicato in:Sci Rep
Autori principali: Rezey, Alyssa C., Gerlach, Brennan D., Wang, Ruping, Liao, Guoning, Tang, Dale D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6525254/
https://ncbi.nlm.nih.gov/pubmed/31101859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-43927-8
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