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Plk1 Mediates Paxillin Phosphorylation (Ser-272), Centrosome Maturation, and Airway Smooth Muscle Layer Thickening in Allergic Asthma

Allergic asthma is characterized by airway smooth muscle layer thickening, which is largely attributed to cell division that requires the formation of centrosomes. Centrosomes play a pivotal role in regulating bipolar spindle formation and cell division. Before mitosis, centrosomes undergo maturatio...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Rezey, Alyssa C., Gerlach, Brennan D., Wang, Ruping, Liao, Guoning, Tang, Dale D.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6525254/
https://ncbi.nlm.nih.gov/pubmed/31101859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-43927-8
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