Plk1 Mediates Paxillin Phosphorylation (Ser-272), Centrosome Maturation, and Airway Smooth Muscle Layer Thickening in Allergic Asthma

Allergic asthma is characterized by airway smooth muscle layer thickening, which is largely attributed to cell division that requires the formation of centrosomes. Centrosomes play a pivotal role in regulating bipolar spindle formation and cell division. Before mitosis, centrosomes undergo maturatio...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Rezey, Alyssa C., Gerlach, Brennan D., Wang, Ruping, Liao, Guoning, Tang, Dale D.
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2019
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6525254/
https://ncbi.nlm.nih.gov/pubmed/31101859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-43927-8
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